BIOL 1111 Lecture Notes - Ultrafiltration, Inulin, Colligative Properties
1 Feb 2013
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Document Summary
Functions of the human kidney: main function: maintain volume and solute concentration in extracellular fluid, also, excretes substances, makes glucose, nh3, and hormones. Control of fluid compartments: fluid is compartmentalized in the human body. Intracellular fluid: holds about 2/3 of body fluid. Extracellular fluid: holds about 1/3 of body fluid: interstitial fluid (isf) between cells & outside of bloodstream, ultrafiltrate of plasma but doesn"t contain many proteins, intravascular fluid (ivf) includes plasma & rbc, transcellular fluids (tcf) special glandular secretions (tears, statistics: 20-25% total cardiac output is blood sent to kidney. ~180 l are filtered thru kidney (enter bowman"s capsule) but only 1-1. 5. L are excreted per day: water is freely exchangeable among all body compartments, but distribution is controlled, solute distribution. By solute concentration, ie osmotic pressure (a colligative property) By hydrostatic pressure pressure created by h2o presence. Means of solute migration: permeability transporters. 3. ion pumps (a transporter) and membrane potential.
