BIOL 1111 Lecture Notes - Lecture 3: Intermembrane Space, Signal Peptide, Oxidative Phosphorylation
Document Summary
Mitochondria shown in the left is double membrane structure- oute(cid:396) a(cid:374)d i(cid:374)(cid:374)e(cid:396) (cid:373)e(cid:373)(cid:271)(cid:396)a(cid:374)e that"s folded into cristae. It surrounds (two reals compartments) space between the two membranes (intermembrane space), inside inner membrane is the matrix (where oxidative phosphorylation occurs) Proteins exist in intermembrane as well- as you know mitochondria have microbial origins (have. Dna), it encodes for some enzymes trna and other molecules it needs to survive. Dna has lots most of its genes though, those genes migrated into our nucleus. There has been an exchange of genetic information. This is interesting but also has a problem. The problem is now instead of making then proteins within the mitochondria it made in the cytoplasm and they have to transfer it (very complex ) Signals proteins to make them go to the mitochondria (many signals) important to get it there but important it goes to the right place. Proteins going to mitochondria have a mitochondria signal peptide.