BIOL 2070 Lecture Notes - Lecture 3: Brainstem, P53, Cervical Cancer

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1930: began to be called viruses instead of contagious fluid (virus is latin for poison) Many interactions between receptors and the virus cause a strong bond between the virus and host cell: receptor sites: bacteriapahages cell wall of host or fimbriae or flagella. Animal viruses plasma membrane of host cells: phage therapy: using bacteriophages to treat bacterial infections, oncolytic: tumour destroying viruses. Is determined through the use of electron microscopy: range from 20 to 1000 nm in length. The capsid provides resistance to nucleases and promotes the viruses attachment to host cells: the immune system produces antibodies (proteins that interact with the surface receptors/proteins of viruses) when a viral infection occurs. Virus surface receptors/proteins have a high mutation rate and therefore antibodies can"t interact with them after a mutation and the infection continues. General morphology: helical viruses: resemble long rods that may be rigid or flexible. Rabies and ebola hemorrhagic fever: polyhedral viruses: many sided virus.

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