Anatomy and Cell Biology 2221 Lecture Notes - Lecture 15: Axon Guidance, Hard Wired, Midbrain Tectum
Document Summary
Have a 100 000 million neurone in our brain and spinal cord! Problem of connectivity in the nervous system! How do neurons one side of the brain (e. g. in motor cortex) send an axon to another part of the brain! Has really far distances to travel ! Neurons motor cortex - midline-striatum - cerebellum - down the brainstem to the cervical spinal cord - innervates lumber part of the spinal cord ! Axon bi-passes all sorts of potential ! In the spinal cord par8cular types of neurons are arranged in columns. Sensory neurons are dorsal and motor neurons are ventral. Label the rostral to caudal motor neurons a- d they target the muscle in the. Order of neurons in the projec8ng eld is re ected by the order of connec8ons. More rostral motor neurons target more rostrally in the muscle (topographic following pa>ern (1- 4) in the receptor eld mapping)