Anatomy and Cell Biology 3309 Lecture Notes - Lecture 11: Connective Tissue, Hyperelastic Material, Elastic Fiber

• School: Western University
• Department: Anatomy and Cell Biology
• Course: Anatomy and Cell Biology 3309
• Professor: Kem Rogers

Document Summary

Connective tissue and its derivatives: co(cid:374)(cid:374)e(cid:272)ti(cid:448)e tissue part i: e(cid:454)tra(cid:272)ellular matri(cid:454) Collagen: of one big protein (bind to eosin) arrows are pointed to one band of collagen the fiber is evenly stained with h&e stains as pink (cid:271)a(cid:374)ds (cid:271)e(cid:272)ause the(cid:455)"re made type 1 collagen: 280-300nm in length, 1. 5nm in diameter: electron micrograph, top left corner: collagen cut longitudinally, bottom right: collagen cross section, notice the striated/banded appearance (only seen with high resolution, very hydrophilic, fundamental unit of collagen: alpha chain (a. k. a. procollagen) Ehlers-danlos syndrome (hyper-elasticity of the skin: fibrillar: thread like; filamentous. Fibril grouping of collagen molecules: fi(cid:271)er grouping of many fibrils, bu(cid:374)dle grouping of many fibers reticular fibers in the lamina fibroreticularis type iv in the lamina densa. 3 layers of basement membrane: lamina rara, lamina densa (basal lamina), lamina fibroreticularis note: homogenous basement membrane underlying the epithelium. Lymph nodes are small, bean- highlighted using silver stain found in bone marrow, lymph nodes.