Anatomy and Cell Biology 3309 Lecture Notes - Lecture 38: Intracellular Receptor, Granin, Pregnenolone
3 Dec 2014
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Document Summary
Endocrine glands: endocrine cells in various difference organs that produce specific hormones, they are perfused with fenestrated capillaries so that hormones have easy access to blood stream, secrete products (hormones) into circulation through fenestrated capillaries, the products act specifically on target cells at distant sites through receptor mediated signaling to elicit different events, ductless glands, organs that have a purely endocrine function are: adrenal, thyroid, parathyroid, pituitary, pineal, organs that have endocrine and other functions are: testes, ovaries, pancreas, hormone: a chemical product that is transported by the blood or body fluids and has a specific regulatory effect on cells remote from its origin, protein hormones: bind transmembrane receptors to cause a conformational change that effects the physiological response, or the transcription of genes, steroid hormones: relatively small and hydrophobic, brought on carrier proteins in bloodstream, diffuse through membrane and bind to nuclear receptor on dna, different genes have response elements to different hormones.
