Anatomy and Cell Biology 4429A Lecture Notes - Lecture 17: Centromere, Apoptosis, Reverse Transcriptase
12 Jan 2018
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Found that cells are immortal and divided more the 1000x. People could not replicate his cells, and believed at that point that cells could be immortal. *he was wrong: his lab kept adding cells because they did(cid:374)"t (cid:449)a(cid:374)t to disappoint him now that he was already famous. The wi-(cid:1007)8 (cid:272)ells he (cid:373)ade are (cid:272)urre(cid:374)tl(cid:455) used to (cid:373)ake (cid:448)a(cid:272)(cid:272)i(cid:374)es. He also tried to repli(cid:272)ate carrel"s (cid:272)ells, (cid:271)ut his cells showed the normal senescence pattern (initial linear growth that plateaued and became senescent). His experiment then showed that senescence is a natural occurrence and all cells underwent this process. He started with two fibroblast cell lines one from males and one from females. The two had different number of doubling already performed (female cells underwent 10 doublings, and male cells underwent. The two cell types were mixed in a 1:1 ratio, and they could be distinguished by the presence of a.
