Anatomy and Cell Biology 4451F/G Lecture Notes - Lecture 1: Transmissible Spongiform Encephalopathy, Model Organism, Aplysia
Lecture 1 - Introduction
What is Integrative Neuroscience?
From molecules to behavior – Integration of different levels of analysis
The output of the brain is the behaviour – we need to understand how physiological processes in the
brain generate behavior
What animal models?
- Neurotransmitter, receptors, kinases, phosphatases etc. are mostly highly conserved
- There is a high number of homologous genes between C. elegans and humans
- The loer the aial odel, the ore iasie/geetic approaches are possible (and the
cheaper the animal model)...but the less it might be applicable to humans/primates
- Genetic models: C. elegans, Drosophila, Zebrafish, Mouse
- Circuitry models: Aplysia, Crab, Fish, Mouse/Rat
Mon, Oct. 16 unit 1
Wed, Oct. 198
Fri, Oct. 20
Intro: learning and Memory
Research into Cognitive Function
Learning experiment: Protocol assignment
SS
SS
SS, students
Mon, Oct. 23 unit 2
Wed, Oct. 25
Friday Oct 27
Intro: Reward and Addiction
Research on Addiction
Paper Critique posted
SS
SL
Mon, Oct. 30 unit 3
Wed, Nov. 01
Intro: Motor systems
Research on Parkinsons Disease
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VP
Mon, Nov. 06 unit 4
Wed, Nov. 08
Intro: Neuroendocrine system
Stress, Stress Disorders
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SL
Mon, Nov. 13
Wed, Nov. 15
SFN – Conference (no class)
SFN – Conference (no class)
Mon, Nov. 20 unit 5
Wed, Nov. 22
Intro: Cell death – Apoptosis versus Necrosis
Neuroinflammation in Stroke and AD
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SW
Mon, Nov. 27 unit 6
Wed, Nov. 29
Intro: Neurodevelopment and Regeneration of Neurons
Research in Spinal Cord Development & Regeneration
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AB
Mon, Dec. 04
Wed, Dec. 06
Research on neurodegenerative diseases (Prion diseases)
Research on hearing loss
MA
BA
Mon, Oct. 16 unit 1
Intro: learning and Memory
SS
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