Anatomy and Cell Biology 4451F/G Lecture Notes - Lecture 1: Transmissible Spongiform Encephalopathy, Model Organism, Aplysia

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Lecture 1 - Introduction
What is Integrative Neuroscience?
From molecules to behavior Integration of different levels of analysis
The output of the brain is the behaviour we need to understand how physiological processes in the
brain generate behavior
What animal models?
- Neurotransmitter, receptors, kinases, phosphatases etc. are mostly highly conserved
- There is a high number of homologous genes between C. elegans and humans
- The loer the aial odel, the ore iasie/geetic approaches are possible (and the
cheaper the animal model)...but the less it might be applicable to humans/primates
- Genetic models: C. elegans, Drosophila, Zebrafish, Mouse
- Circuitry models: Aplysia, Crab, Fish, Mouse/Rat
Mon, Oct. 16 unit 1
Wed, Oct. 198
Fri, Oct. 20
Intro: learning and Memory
Research into Cognitive Function
Learning experiment: Protocol assignment
SS
SS
SS, students
Mon, Oct. 23 unit 2
Wed, Oct. 25
Friday Oct 27
Intro: Reward and Addiction
Research on Addiction
Paper Critique posted
SS
SL
Mon, Oct. 30 unit 3
Wed, Nov. 01
Intro: Motor systems
Research on Parkinsons Disease
SS
VP
Mon, Nov. 06 unit 4
Wed, Nov. 08
Intro: Neuroendocrine system
Stress, Stress Disorders
SS
SL
Mon, Nov. 13
Wed, Nov. 15
SFN Conference (no class)
SFN Conference (no class)
Mon, Nov. 20 unit 5
Wed, Nov. 22
Intro: Cell death Apoptosis versus Necrosis
Neuroinflammation in Stroke and AD
SS
SW
Mon, Nov. 27 unit 6
Wed, Nov. 29
Intro: Neurodevelopment and Regeneration of Neurons
Research in Spinal Cord Development & Regeneration
SS
AB
Mon, Dec. 04
Wed, Dec. 06
Research on neurodegenerative diseases (Prion diseases)
Research on hearing loss
MA
BA
Mon, Oct. 16 unit 1
Intro: learning and Memory
SS
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