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Lecture

Anatomy and Cell Biology 4461B Lecture Notes - Malignant Transformation, Meninges, Desmosome


Department
Anatomy and Cell Biology
Course Code
ANAT 4461B
Professor
Geordie Shepherd

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LP Lecture 1: Introduction to Melanoma
Skin Cancer - most common cancer is Canada
2 Categories
Non-Melanoma Skin Cancer
Includes basal cell cancer and squamous cell cancer
Most common
Cancer of the kertinocyte
Melanoma
Less common but more fatal
Cancer of the melanocyte
Incidence rates continue to rise and men and women
Risk Factors
Overexposure to artificial UV light (tanning beds) is the primary cause of skin cancer
Other risk factors
Light skin, eyes or hair
Skin that burns or freckles easily and tans poorly
Personal history of skin cancer
Strong family history of skin cancer
Having many moles
Sun exposure
Integumentary System
Largest organ; 15-20% of mass
Major functions
Barrier
Immunologic
Homeostasis
Sensory
Endocrine
Excretion
Vitamin Production
2 layers separated by a basement membrane
Epidermis
Keratinized stratified squamous epithelium
Derived from ectoderm
Avascular
4 major layers
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