Anatomy and Cell Biology 3309 Lecture Notes - Lecture 21: Cytoskeleton, Glycoprotein, Lysosome
28 Dec 2017
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Red bone marrow: where majority of blood formation occurs. When blood is taken, anti-coagulated and spun down at low speed: plasma at top, buffy coat representing all the formed elements in the blood stream (other than erythrocytes, rbcs at the bottom. Take bone marrow out of animals and separate cells out into individual cells in suspension and plate with agarose: cells divide and give rise to colonies of a particular cell type (rbcs, neutrophils, etc. ) There is a pluripotent stem cell a stem cell that can do everything and can reproduce itself agarose but they didn"t know what cell it was until it grew into a colony. Stem cells are self-replicating to maintain their population and give rise to differentiated cell lineages monocyte and megakaryocytic. Blood formation starts in the yolk sac when the cardiovascular system is being established and moves into the liver and spleen. Blood formation occurs in the bone marrow.
