Anatomy and Cell Biology 4429A Lecture Notes - Neuroprotection, Prnp
22 Dec 2011
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There is also a familial from that counts for a tiny fraction of this disease. If someone had cjd and was eaten, the consumer could get it as well: mad cow - cows developed this by eating meal which contained infected nervous systems of sheep. These sheep had scrapey (called this because sheep scraped off their fur when they had it). Yeast are similar to prions - have two different conformations that do two very different things. Nobel prize was given for discovering this slow virus that caused these diseases, however prion diseases are not caused by a virus! Prions: pure proteins, have no dna, disease with a very long latency period because it"s a second order process. When disease symptoms start to show, the disease is already very advanced: disease is associated with a change from prpc (a normal surface glycoprotein) to. Prsc, an infectious protein in the absence of nucleic acid.
