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Lecture 16

Anthropology 2235A/B Lecture Notes - Lecture 16: Combined Dna Index System, Restriction Fragment Length Polymorphism


Department
Anthropology
Course Code
ANTH 2235A/B
Professor
Eldon Molto
Lecture
16

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Lecture 16 Legislation and the DNA Wars
With the power of DNA for individuation it was decided that new controls
and legislation was in order to deal with potential problems
With labs using RFLPs and some STRs the problem of conformity emerged
and these were addressed by the National Research Council and the
Technical Working Group on DNA Analysis and Methods
NRC I and II
TWGDAM
DNA Databases
o Initially attempts were made to develop RFLP databases but
quickly STRs were replacing RFLPs
o In 1995 the FSS in the UK developed first forensic database
o In 1998 FBI launches CODIS (CObined DNA Index System, linking
all forensic labs
o In 2000 in Canada the National DNA Databank was launched,
connected to all labs in Canada and to Codis
o These databanks are used to determine random match probabilities
and to link convicted offenders to crime scenes
Industry-Wide Standardization
o Large majority of products/services conform to same standards
o Pertains when consensus agreements between practitioners (e.g.
TWGDAM)
o Aim is enhanced product quality
o End-users have more confidence in products/services that conform
o Assurance of conformity provided by audits carried out by
independent bodies
DNA Standards
o T(S)WGDAM (Technical (Scientific) Working Group on DNA
Analysis Methods) ‘guidelines’
o Now SWGDAM
o Laboratory Accreditation
ASCLD/LAB
Standards Council of Canada (SCC)
Note both ASCLD and SCC use the same guidelines ISO-
17025
o Legislation
DNA Advisory Board (DAB)
Certification of analysts (ABC)