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Lecture 11

Anthropology 2235A/B Lecture Notes - Lecture 11: Human Genome Project, Forensic Science

Course Code
ANTH 2235A/B
Eldon Molto

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Lecture 11 DNA in Forensic Science: Introduction and Historical
o The field of genetics has a long history
o Key developments are the understanding of genetic transmission in
families and populations and the understanding of the molecular
structure of genetic transmission
o Together with advances in technology, these form the foundation of
modern forensic genetic analysis
o PCR: Polymerase Chain Reaction
o Field of forensic science has changed dramatically in the past 20
years due to genetic science and the admissibility of science in the
o Still it is important to have a historical perspective
Historical Snapshots
o 1865 Mendel's Laws (1900 discovered)
o 1908 Hardy-Weinberg Theorem
o 1953 Watson-Crick discovery of DNA
o 1977 Sequencing (Sanger Method)
o 1981 human mitochondrial genome completely sequence
o 1985 PCR invented
o 1991 1st paper on STRs, DNA identification Act and TWGDAM
o 1995-1999 1st DNA STR databases in Britain, US and Canada
o 2002 SNP technology
o 2003 Human Genome Project completed