Biochemistry 2280A Lecture : Fatty Acid Biosynthesis

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orchidotter238

21 Dec 2011

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Document Summary

Eating food blood glucose/liver is satisfied eat ice-cream adds more sugar but the livers already saturated; it will end up as acetyl-coa; don t need atp its made into fat. Once it is in the cytosol we can use it to make fatty acids. Taking 2 carbon units and adding them onto each other to make a larger molecule. Glucagon binds to a receptor = carries out the signal, glucagon doesn t directly interact with the lipases (signal is the full line) Insulin is in the blood promote energy storage so insulin turns off the process of breaking down triacylglycerol interacting through a bunch of intermediates to do so. The intermediates in glycolysis and citric acid cycle are not always used for atp generation can be used to make other things. One glucose molecule probably wont get all 30 atp because some carbons will be lost along the way. Cholesterol is in our membrane in order to regulate the fluidity.

Related Questions

How does catabolism of glucose from dietary carbohydrates link to fatty acid synthesis?

Choose one or more:

A. Catabolism of excess dietary carbohydrates raises the energy charge of the cell, which slows the flux of the citric acid cycle.

B. Glycolytic intermediates can be used as substrates for fatty acid and triacylglycerol synthesis.

C. Increased flux of the citric acid cycle produces NADH, which can be used for fatty acid synthesis.

D. Catabolism of excess dietary carbohydrates reduces fatty acid oxidation.

Where does each of these processes take place within the cell? Possible answers: cytosol, mitochondrial matrix, lysosome, nucleus, inner mitochondrial membrane, outer mitochondrial membrane, mitochondrial intermembrane space

1. Glycolysis cytosol

2. citric acid cycle Mitochondrial Matrix

3. conversion of pyruvate to activated acetyl groups

4. oxidation of fatty acids to acetyl CoA

5. glycogen breakdown

6. release of fatty acids from triacylglycerols

7. oxidative phosphorylation