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Eric Ball (118)
Lecture

Gluconeogenesis

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Department
Biochemistry
Course
Biochemistry 2280A
Professor
Eric Ball
Semester
Fall

Description
GluconeogenesisItcan use amino acids citric acid cycle intermediates etc to make this work At some pointuse all glycogen storesliver does gluconeogensis in order to provide energy for the brain and rest of the body brain still needs glucose Converting the bottom molecules into oxaloacetate and into glucose Delta G is a very negative valuecan take pyruvate and go back to glucose If glycolysis is so energetically favourable how can liver cells synthesize glucose from pyruvate Certain reactions proceed by completely different mechanisms in the glycolysis and gluconeogenesis directions Enzymes CANT change the way of the reaction3 of the reactions were noneequilibrium reactions Concentrationslower amount of glucosehigher amount of pyruvatethis alone wont make it favourable different enzymes catalyze different reactions in different ways need different enzymes to do the reverse reaction cant use the same reactionmechanism to go in the opposite way therefore we need to
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