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Biochemistry 2280A Lecture : Translation

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orchidotter238
29 Dec 2011
School
Western University
Department
Biochemistry
Course
Biochemistry 2280A
Professor
Eric Ball

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Document Summary

Figure 7-33 assumes that translation has already started. A peptidyl-trna is in the p site of the ribosome. Aaminoacyl-trna binds to the a site of the ribosome. Requires base pairing between the trna and the codon. We got 5 end and 3 end of rna. We got peptidyl trna in the p site. Amino acyl trna comes on a site of ribosome. This requires basepairing between trna and codon with exception of wobble. Its not just any aminacyl trna it has to be recognized through base pairing. ribosome can tell base pairing is going on or not. The energy grom esterbonds of the peptidyl-trna in the p site is used to form a new peptide bond between the amino acids in the a and p sites. The erngy from the bond is used to make peptide bond between amino acid 3 and 4 here.

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Related Questions

Hi guys, could you help me on this question?

Every ribosome has three tRNA binding sites: the A site, the Psite, and the E site. For the following sentences, select thecorrect site from the drop-down menu.

What happens when a stop codon is reached by a ribosome?

A termination tRNAter binds to the codon and the growing peptide is transferred to it. When the peptidyl-tRNAterreaches the P site, the ribosome is signaled to release the protein. The ribosome then is likely to dissociate.

A release factor binds to the codon and is used to release the growing peptide from the P site tRNA.

A termination tRNAter binds to the codon and the growing peptide is transferred to it. When the peptidyl-tRNAterreaches the P site, the ribosome dissociates. A separate peptidyl transferase then releases the protein from tRNAter.

A release factor binds to the codon and the ribosome dissociates. A separate peptidyl transferase then releases the protein from the last tRNA to which was attached.

A termination tRNAter binds to the codon and is used to release the growing peptide from the P site tRNA. The ribosome then is likely to dissociate.