Biochemistry 2280A Lecture Notes - Lecture 19: Metachromatic Leukodystrophy, European Corn Borer, Classical Genetics

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Dna technology can help solve lots of catastrophes. Dna technology can"t fix: celestial collision, nuclear catastrophe, trump. What are some catastrophes facing humankind: global warming, food crisis, water crisis, global pandemics: ebola, sars, avian flu, antibiotic resistant bacteria. Definition: the techniques which recombine dna fragments from different sources into new molecules with unique features. Classical genetics: slow: limited by the breeding time of the organism and change genetic events, sometimes a year, exchange of genetic material is limited to breeding species. Recombinant dna technology: rapid: as quick as a few days in some organisms, no limitations, can put dna into whatever we want when we use bacteria. Significance of recombinant dna technology: research: key tool to understand cell and molecular structure/function, understand proteins, biotechnology: major impact on society. Drug production and design: human insulin, human growth hormones, vaccines, artemisinin (malaria) Detect pathogens and disease causing gene through their dna significance: get blood sample and look at gene.

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