Biochemistry 2280A Lecture Notes - Lecture 21: Interferon Alfa-2B, Branch Point, Intron
25 Mar 2017
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Lecture 21: formation of mrnas of a after the sequence) Process: mrna export from the nucleus, translation of the mrna. 5" end of eukaryote mrna has a 7 methylguanosine (7 methyl g) importance of cap: 30 bases downstream from that and then adds the poly a tail. Required for: mrna export, translation importance of tail: translated they prevent the exonucleases from degrading the mrna. Protein encoding sequences (exons) are interrupted by non coding sequences(introns) B globin, 3 exons, 2 introns 2000 nucleotides is total genes. Most of gene is introns non coding sequences. Human factor 8- involved in blood clotting. Allows for additional complexity in the genome. Clicker q: proteins are related as they can share different exons. Assuming the 5; most exons is always expressed and splicing occurs in a linear fashion (cid:523)5" to (cid:885)"(cid:524) how many protein products could be made from the following gene. Exon 1: alone (no splicing) one product.
