Biochemistry 2280A Lecture Notes - Lecture 17: Allolactose, Transfer Rna, Raffinose
16 Jan 2018
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Document Summary
The human genomes encodes ~21,000 protein encoding genes. In any cell type, less than 10,000 are expresses at a time. In those that are expressed, they are expressed at different levels. Expression of corrects is essential in growth and development by producing differentiated cell. Genes expressed in the brain, may not be expressed in liver cells, making cell types and organisms unique from each other. Most diseases are due to altered expression in one or more genes. By therapeutically manipulating gene expression, there is a potential to prevent or reverse diseases i. e inhibition of gene expression of a pathogen. The flow of genetic information from dna to rna to proteins. Gene expression in a eukaryotic cells can be regulated at many step, >8 steps. Regulation targets early steps, initiation of termination is often targeted. Only occurs in eukaryotes, prokaryotes do not have to process rna before translation mrna exportation to the cytoplasm.
