Biochemistry 2280A Lecture Notes - Lecture 17: Consensus Sequence, Allolactose, Conformational Change
9 Aug 2018
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Major topics for brandl: 1) gene expression, 2) recombinant dna technology, 3) molecular basis of cancer, objectives: Increase your ability to obtain and use biochemical information provided in different formats: understand mechanisms of information flow in the cell, think critically about why biochemical mechanisms occur as they do, consider how structure relates to function. Introduce you to concepts of experimental design: describe how biochemistry relates to human disease. Include structural proteins, rna polymerases, dna repair enzymes, etc: cells also produce specialized protein for their differentiated function, gene expressio(cid:374) (cid:272)a(cid:374) (cid:271)e studied (cid:271)(cid:455) (cid:272)atalogi(cid:374)g (cid:272)ell"s rnas, i(cid:374)(cid:272)ludi(cid:374)g (cid:373)rna. If we can fix gene expression we can cure disease that"s (cid:449)h(cid:455) a lot of people a(cid:396)e interested in trying to understand gene expression. The central dogma: genetic information flows from dna to rna to protein, this was proposed many years ago (francis and crick). Dna transcribed to rna which is then translated to protein.
