Biochemistry 2280A Lecture Notes - Lecture 13: Fatty Acid Metabolism, Ketone Bodies, Ketone
27 Mar 2019
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Topic 13 learning objectives: effects of insulin and glucagon, metabolic implications of key energy indicators, metabolic responses to prolonged fasting, diabetes mellitus. It will taper off when fatty acid metabolism picks up to full speed: now you"re living only on fatty acid metabolism. An average person can live for 2-3 months on fatty acid metabolism: after your triacylglycerol storage has gone your body goes back to break down muscle. Healthy response to high blood glucose: lots of glucose is around healthy person will respond by removing it and metabolising it, high glucose = insulin. Response is to shut down triacylglycerol breakdown, promote glycogens storage and glycolysis, promote ppp, etc: as a result, glucose is being used by all these tissues and will lower to healthy levels. Type 1 diabetes: cells in your pancreas that make insulin have been destroyed in your youth, no insulin gets produced, high blood glucose isn"t recognizable.
