Biochemistry 2280A Lecture Notes - Lecture 22: Polyadenylation, Asteroid Family

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Topic 22: gene expression overview lecture notes. In any cell types less than 10,000 are expressed. The human genome encodes ~21,000 protein encoding genes. The expression of the correct genes is essential for growth and. Crucial that genes are expressed at the right levels, growth and differentiation differentiation requires that the correct genes come on and their levels of gene expression are correct. Genomes are the same, but the proteins expressed are really different. Top right blue expressed highly in liver but not brain. Different cells have to turn on different genes to different extents to make the right tissues. Almost any disease will have one or more genes with an incorrect expression. If you can alter gene expression to get it back to normal, should be able to cure a disease. Our dna is converted by transcription to rna which is then translated. Steps at which gene expression can be regulated: transcription.

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