Biochemistry 2280A Lecture 1: Chemical Basis of Life

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Biochemistry: study of living systems and how molecules interact. Dogma represents the flow of information whereby genetic information that is stored in our. Dna as a sequence of nucleotides gets transformed into phenotypic information in the form of proteins. How genetic information can be passed on as cells divide and how dna can be replicated as cells divide. Protein encoding information is stored in the genes in the dna and it is a function of the nucleotide sequence. Transcription: copy of one strand is made into rna then nucleotides in rna specifies the synthesis of a protein (sequence of amino acids translation) Enzymes, structural proteins, transport, motor, storage, gene regulatory, receptor, signal. Dna can encode 20 different amino acids to make up proteins. Triplets of nucleotides: codons each specifies an addition of an amino acid into the peptide chain during translation. Orchestrated by ribosome trna have anticodon that recognizes a particular codon on mrna.

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