Biochemistry 3380G Lecture Notes - Catabolism, Energy Carrier, Metabolic Pathway

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Metabolism is the sum of all reactions that go in the cell (half of them being catabolic, half anabolic). Metabolic pathways are a series of reactions coupled together that form a new product. Flux is the rate of conversion from the reactants to the final product of a metabolic pathway. This conversion is efficient when the net g for the whole pathway is negative. Generally, a metabolic pathway consists of mostly reactions at equilibrium ( g 0), but some are reactions with great spontaneity ( g << 0) and are considered crucial. With equilibrium reactions, where g 0, changes in concentration heavily influence the extent of the reaction by way of le chatelier"s principle. Enzymes used here can catalyze both the forward and reverse reactions and are considered reversible. With highly spontaneous reactions, where g << 0, adding products has little to no effect on the equilibrium of the reaction (which is hardly observed).

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