Biology 1001A Lecture Notes - Lecture 6: Primase, Telomere, Adenine
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1 May 2013
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Misunderstanding because researchers defined functional as anything that looks like it could be expressed. It might be functional, but it"s not function to make you. Double helical structure of dna with two antiparallel backbones. Each single strand of dna has a 3" and 5" end which confers. Polarity on dna backbones and gives it a sort of direction . 3" end has a free hydroxyl (oh) Two strands of double helix run antiparallel. Replication is semi-conservative -> know meselson & stahl. Dna polymerase adds incoming nucleotide to a free oh on the 3" end of the dna. Every dna polymerase does only one kind of elongation: extends the 3" end. Replisomes replicate one strand continuously, one discontinuously. Replisomes are active at the replication fork. Two polymerase are going simultaneously to extend the two strands. However you can only go from the 3" end, but the strands of parent dna are antiparallel; thus going in different directions.
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