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L10 – Meiosis

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Biology 1001A
Tom Haffie

L10 – Meiosis List of Mechanisms by which Meiosis contributes to genomic diversity 1. Recombination during meiosis (mechanism contributing to copy number variation) 2. Unequal crossing over of alleles in recombination gives copy number variation (CNV) 3. Random fertilization combinations of egg & sperm Zygotes bring DNA from two different cells into the same cell Homologous chromosomes carry the same genes w/ different alleles - Homologues have the same genes in the same places - Differ in alleles Divisions of Meiosis Meiosis 1 – reductional division of meiosis (diploid  haploid) Meiosis 2 – differs in amount of DNA (2C  1C) - only makes gametes in some organisms (humans, some animals) - other products of meiosis can be spores (plants) which replicate by mitosis to produce gametophytes to give gametes by mitosis - plants make gametes by mitosis - fungi meiosis produces spores  gametophyte  gametes  zygote  meiosis immediately w/o dividing Recombination of paired homologues - molecular biology of recombination with respect to DNA backbones & breakage of bonds to cut and paste backbones - highly controlled enzymatic process w/ recombination enzymes - DNA recombinati
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