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2011.09.28 - Bio 1001 Lecture Notes.docx

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Biology 1001A
Tom Haffie

Biology Lecture 6: Eukaryotic Recombination Clicker Question: Which type of bacterial genetic exchange involves donor cells that are dead? A. Conjugation B. Transduction C. Transformation D. Both A and B E. Both B and C  Recombination enzymes “cut” and “paste” both DNA backbones.  Two recombination events would have to take place in order for the B+ allele to end up on the recipient chromosome.  Transposons can send a copy of themselves on a plasmid.  Transposons can replicate and recombine and send a copy to another target sequence.  Plasmids can carry resistance genes to recipient cells. Clicker Question: My son Jay has a unique combination of alleles as a result of “cutting and pasting” DNA backbones. When did this recombination occur? A. When Jay was a newly fertilized, single celled zygote. B. When Jay was a developing fetus. C. When Jay reached sexual maturity. D. When Jay’s parents made gametes. Eukaryotic Recombination:  Zygotes bring DNA from two parents into close proximity.  Homologus chromosomes carry the same genes, but different alleles.  In prophase of meiosis I, homologues pair and recombine.  Recombination happens in prophase of meiosis I.  “Crossing Over” is
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