Biology 1002B Lecture Notes - Lecture 6: Endergonic Reaction, Exergonic Reaction, Reaction Rate

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14 Jul 2014
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Spontaneous reactions can occur over a really long time. If you add an enzyme, then the reaction speeds up. Enzymes usually increase the rate of the reaction 1012-1020 times. Enzyme is a specific group of proteins that catalyze reactions, but they do not get consumed (definition of a catalyst). Conversion of a to b is exergonic reaction; enzyme can speed up the reaction. Conversion of b to c is an endergonic reaction, can"t use an enzyme, instead energy coupling is needed. It cannot make an endergonic reaction into an exergonic reaction. To drive the endergonic reaction, you need energy from atp breakdown. The free energy of the products is negative, than the starting molecule. For the reaction to proceed, they need to acquire free energy from the surroundings. The transition state is where they are in a higher level of free energy. This is when the bonds are ready to break.

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