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Lecture 7

Lecture 7: Membrane Biology

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Biology 1002B
Niki Sharan

Lecture 7Membrane Biology y Membranes are not only lipidsmany membranes are 50 or more proteinsLipid Bilayery All biological membranes consist of a lipid bilayer y Lipid molecules consists of a hydrophilic head and a hydrophobic fattyacid taily The part of the lipid that interacts with the aqueouspolar environment is hydrophilicy The internal part the fatty acids are hydrophobicthe tendency for hydrophobic molecules to want to group together is a spontaneous reactionlow energy statey Hydrophobic and hydrophilic in one moleculeamphipathicmolecules which are both polar and nonpolary Detergents are an example of amphipathic moleculessolubilize both hydrophobic and hydrophilic molecules FattyAcid Structurey Fatty acids are important in dictating the structural function of a membraney Saturated fatty acids are saturated with hydrogenslinear moleculey Unsaturated fatty acids have fewer than the total possible amount of hydrogensmolecule is no longer linear consists of at least one bendo transunsaturated vs cisunsaturatedy These molecules are very diversefatty acids can vary based on the length and positioning of the carboncarbon double bondsthis can change the characteristics of any specific fatty acidy The structure of fatty acids are important because they affect the fluidity of the membranehow liquid the membrane isy Membranes are involved in transport electron transport occurs within a membrane so keeping the membrane in the right fluidity is vital to lifey The more unsaturated the membrane the more fluid it will be if both saturated and unsaturated are compared at the same temperaturey Humans are endothermic as we have control over our temperaturey Ectothermsreptiles plants bacteriabody temperature is dictated by environmental temperaturesy Maintaining fluidity and adjusting the levels of saturation may not be as important for humans but it is really important for organisms such as plants and bacteria because their growth temperature can change such that their membranes can become rocksolid or they can become too fluid
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