Biology 1202B Lecture Notes - Lecture 12: Mutation, Chromatin, Deoxyribonuclease
1 May 2017
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12. 1a experiments began when griffith found a substance that could. S - smooth strain - polysaccharide capsule surrounding each cell and forms colonies that appear smooth and glossy. S strain was the capsule responsible for virulence the virulent s form: transforming principle and the process of genetic change transformation - the conversion of r bacteria to s bacteria. Injected living r bacteria along with health-killed s bacteria. 12. 1b avery and his coworkers identified dna as the molecule that transforms avirulent rough. Infected separate cultures of e. coli with two types of labelled phages. 12. 2 dna structure: watson and crick discovered the structure of dna. Dna has a helical structure similar to a spiral staircase. 12. 3 dna replication: complementary base-pairing explains how dna replicates, the semi-conservative model meaning that one of the strands is new while the other (which served as template) is old.
