Biology 2382B Lecture Notes - Phosphotransferase, Galactose, Hydrolase
24 Aug 2013
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5: vesicular traffic of proteins & the golgi apparatus. The golgi complex consists of flattened, disk-like cisternae (stacked tubules) with no ribosomes (somewhat extension of rer, but distinct). There are three types of cisternae in the golgi complex: cis- This gives us two flanked networks of tubules: the cgn faces the rer and the tgn is opposite the rer (faces the plasma membrane). Golgi complex lies in its processing and sorting function of secretory, membrane and lysosomal proteins. Budding is initiated by the recruitment of a small gtp-binding protein to a patch of donor membrane. After being released and shedding its coat, a vesicle fuses with its target membrane in a process that involves the interaction of cognate snare proteins. Membrane associated gtp binding proteins (in combination with membrane cargo proteins) promote the association of copii coat proteins (used for rer to cis-golgi transport) on er membrane.
