Biology 2382B Lecture Notes - Lecture 1: Spindle Apparatus, Biological Membrane, Cell Migration

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Specific functions (kinesin and dynein function: anterograde/retrograde transport, axoneme (cilia and flagella movement, mitosis (mitotic apparatus) Cytoskeleton intricate network of protein filaments that extend throughout the cytoplasm. Microtubules (made of & -tubulin dimers) 25nm thickest. Intermediate filaments 10nm: building subunits depend on the type of cells (e. g. skin cells use keratin as a building subunit) Microfilaments (many actins coming together) 7-9nm thinest: they are different polymers of proteins bonded together. *memorize this slide (networks/roads vs. ropes (pull) vs. Cellular trafficking of organelles things inside cell can move. Biological molecules are 3-dimensional (specific size and shape) and take up space!! When we are talking about what is happening in a cell, we have to think about molecules and the fact that they are happening in 3d space. When the textbook shows simplistic diagrams, appreciate that everything is full. There is no empty space inside a cell.

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