Biology 2581B Lecture Notes - Lecture 20: Bacteriophage, Lac Operon, Lac Repressor
10 May 2016
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20 - synthetic biology: parts, modules and systems: craig venter crated the rst biosynthetic prokaryote microplasmid bacterium = world"s rst synthetic organism. Synthesized a complete genome & transferred it to a host cell. Earlier known as recombinant dna technology or biotech. Construct a biological system (ex: a network or a pathway) using characterized genes & regulatory dna sequences. Goal: achieve the highest ef ciency in the synthetic cell with minimal genome that a cell can functional ef ciently, in a reliable & predictable way. Method: replicate the following areas layers of focus in a synthetic cell, but need to understand how they function rst. 4. physical: cell-to-cell communications, protein interactions or how the cell communicates with other cells & its environment, response to motility, growth (photosynthesis, glycolysis), By the end, the synthetic organism must be able to survive in an unique environment that the scientists impose: synthetic biology can be used at all hierarchy and modular organization.
