Biology 2581B Lecture Notes - Lecture 13: Chronic Myelogenous Leukemia, Spindle Apparatus, Zygote
10 May 2016
School
Department
Course
Professor
Document Summary
Overview: chromosomal rearrangements could happen in any species, they include: Comparing the mouse genome & the human genome: similar at the dna level = similar primary nucleotide sequence. Similar types of genes or genes with similar sequences are both present on the chromosomes: different at the chromosomal level conducted the chromosomal spread to compare the chromosomes of the two species. Chromosomal spread: a comparison of staining patterns of chromosomes. Suggested no conservation between the mouse and human genome. Conclusion of differences: (1) the number of chromosomes in mouse vs human. Chromosomes & genomes = packages of genes. Different species have different package size & content organization, although the contents contained as a whole remains the same (they have different gene & chromosome organizations, but contain the same contents) Each mouse chromosome could be pieced together from different human chromosomes: can reconstruct a genome from a different species, knowing that they share similar gene sequences at the nucleotide level.
