Biology 2581B Lecture Notes - Lecture 18: Rna Editing, Cytochrome C Oxidase Subunit I, Resurrection Plant
14 Jul 2016
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Significant genetic alternations that are often not apparent or obvious given the primary dna sequence alone. Knowing the code is crucial so when it changes it can have a huge impact on the way we perceive information. Cox1 amino acid sequence (vertebrate mitochondrial code) o. Rna editing: ability to edit the underlying information (dna: what we expect: Double-stranded dna (coding strand) single-stranded rna (transcript) The 2 stands should be identical (besides the fact that t = u) Not always true because of rna editing o. If you take a random mitochondrial gene (gene a) and then generate the transcript for that gene on the rna level. After generating the transcripts, many of the c"s get edited (c u) Changes the amino acids that would have predicted for that gene. If we look at the dna sequence for cox1 in this plant and make the transcript and it looks the same. But then the c"s are edited to u"s.
