Biology 2581B Lecture Notes - Lecture 18: Genbank, Embryophyte, International Nucleotide Sequence Database Collaboration

• School: Western University
• Department: Biology
• Course: Biology 2581B
• Professor: Susanne Kohalmi

Document Summary

More on modifications knowing the proper code to read an organisms genome is crucial: amino acid sequence of cox1 is completely different when read using the standard code versus the proper vertebrate mitochondrial code. Rna editing (post transcriptional editing) a molecular process through which some cells can make discrete changes to specific nucleotide sequences within a rna molecule after it has been produced through transcription. Mt. genome undergoes rna editing: for example, rna transcript has many c"s in the sequence get edited to u"s, transcript no longer reflects the dna sequence of the coding strand. *so the dna gene sequence does not always reflect the rna transcript. Why does rna editing even happen? it takes dozens to hundreds of proteins to edit the rna to make 1 protein from it: complex called an editosome, different editosomes for different editing jobs.