Biology 3338A Lecture Notes - Catenin, Gsk-3, Apoptosis
3 Apr 2014
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1: after fertilization, cytoplasm looks different (d, only at stage (i) transcription starts. 2: cell adhesion cell sticks to each other (cadherins, cells like to stick to cells of same type, same cells have greater affinity to each there (will be on inside); less affinity on the outside. If put all together, they will sort and form a hierarchy: hierarchy is formed due to different number of cadherin (if had same number would just form a ball) Pretty close to cell communication: optic cup signals to form lens. Lens induces retina from optic cup: endocrine signalling is important but we won"t really look (not really apparent in embryos, paracrine and juxtacrine, paracrine is signalling of very close cells through secreted molecules. Molecule will drift to nearby cells (1 or 2 away): juxtacrine need membranes of cells to touch. 6: have a cell surface receptor (usually a dimer). Need two receptors are dormant in absent of ligand.
