Biology 1001A Lecture Notes - Lecture 10: Enzyme, Probability Distribution, Base Pair
Document Summary
People could have snps that are no present in the parents. This could results from tautomeric shift, mismatched pairings. Alleles are just different version of the gene; and by gene we means different dna sequence; this difference could just as simple as one base pair. Variation means difference in double stranded dna sequence. Origin in inherent in chemistry of dna, enzymology of replication/repair/recombination/cytoskeleton. Can be influenced by physical, chemical, biological agents/conditions. Origin is undirected with regards to survival value (cell do not know what kind of variation they need; they cannot direct mutation in their favour) One thing that organisms do in response to environmental stress is by reproducing sexually, to produce new variation offspring in hope they will be better adapted to the changing environment. Organisms can modulate how much variation they creates, but they cannot directs it, or choose which variation they want or need. Origin is not randomly distributed around genome.
