Biology 1001A Lecture Notes - Lecture 12: Genotype Frequency, Allele Frequency
12 Dec 2017
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Hardy-wei(cid:374)berg is a (cid:862)(cid:374)ull (cid:373)odel(cid:863: gives us a frame of reference. If the observed frequency matches the expected frequency, then it is at hardy-weinberg. Absolute fitness (w: average number of surviving offspring for a particular genotype. What factors might affect w: reproduction, selection pressure in terms of survival (ability to survive into adulthood, fertility, how good a parent you are, ability to find a mate. Relative fitness (w: standardized absolute fitness to get relative fitness, fittest genotype in a population has w=1 (1 is the fittest genotype you can have, for all other genotypes w = w/wmax. Strength of selection reflects how much genotypes differ in relative fitness. When selection is weak, it takes longer to get rid of the dominant allele than if the selection is strong. Selection against a dominant allele (waa = waa < waa)
