Biology 1001A Lecture Notes - Lecture 10: Sporophyte, Telomere, Mitosis
25 Feb 2016
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Document Summary
Some chemical agents enhance that natural mutagenacy (5-bu) Copy number variation (cnv: insertion or deletions (in/del) Areas in the dna that are repetitive are prone to slippages. Anything that is not a change in the double stranded dna is damage. Tendency of slippage is not the same everywhere. Get from x-ray and also from natural environment unavoidable. Reactive oxygen species damages dna trying to get electrons back that will break your dna. Iodine breaks down very quickly but cs lasts a long time. Iodine becomes concentrated in the thyroid glands and may lead to cancer. Ionizing radiation can cause double strand breaks mutation. Repair can sometimes be sloppy and sometimes a whole section of a chromosome gets deleted. These occur when repairing occurs because of iodine radiation. Gene duplication is one of the fundamental mechanisms of increasing complexity of the genome: leads to the production of gene families, collection of genes doing similar functions at perhaps different developmental times.
