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Biology 1002B Lecture Notes - Noncoding Dna, Dna Replication, Protostome

Course Code
BIOL 1002B
Tom Haffie

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Bio Review 10/24/2012 2:33:00 PM
Delta 32 mutation
Provides HIV protection
Disadvantageous to West Nile
o Trade off
o Mutation at receptor at immune cells
Incomplete dominance
Protostome vs. Dutastome species
o Insects
o Crestations
o Many more than dutosames
Evolution happens by mutation
Mutation occurs
Evolution ensures selective advantage
Change is allele frequency
Know Tree diagrams
Should be able to find MRCA
Should know sequence
HIV fast mutation rate
There is a mutation that makes it harmless
Strains that replicate fast kill host faster
Eukaryotes are only multi cellular
Only multicellular in plants animals and fungi
Only a little bit of susceptible form frequency post-AZT
RNA to DNA to RNA to proteins
Only attacks viruses
Does not inhibit normal DNA replication
C-value enigma
Some less complex forms of life have more DNA
o Due to non-coding DNA
Similar species still have largely different C values
If one allele makes phenotype same as homozygote, complete dominance
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If one allele doesn’t make phenotype same as homozygote, incomplete
If both allele contribute, co-dominance
If the chromosomes replicate the C coefficient doubles, n coefficient doesn’t
C is the amount of DNA in one genome, n is the amount of chromosomes
Transposons move by recombination mechanism
If the cell has non-disjunction and disposition it is unfortunate
Transposon are more complex than insertion sequences (smallest thing that
can move on its own)
Motor proteins are in kinetochore
Homologous chromosomes are same length
C value does not change much within species
Advantage of homochirality is life
Telomeres gotten from gametes
8% essential but not coding
Regulatory sequences
Transposons are mutagenic (usually bad news)
If no sister not a chromatid
Telomeres shorten and when at critical length cell kills itself
If loop on growing happens, addition on top strand
If loop on template happens, deletion
LINEs and SINEs neither CNVs of SNIPs
50% are transposons
Next most CNVs
Mitochondria have circular chromosomes
Chromosomes line up at metaphase plate because they are attached to both
G2 checkpoint makes sure cells are ready to divide
Whether a chromosome is replicated or not has nothing to do with the
amount of telomeres
2 DNA III polymerase on each side
1 DNA I polymerase on each side
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