Biology 1202B Lecture Notes - Lecture 14: Start Codon, Messenger Rna, Transfer Rna

29 views4 pages
2 Apr 2013
Department
Professor
Lecture 14: Translation mRNA Protein
Translation
- The assembly of amino acids into polypeptides
- In prokaryotes this process take place throughout the cell
- In eukaryotes this takes place mostly in the cytoplasm
1. ) mRNA Messenger RNA
- 100s of nucleotides long
- Template for translation
- Read in a 5’ to 3’ orientation
2. ) tRNA Transfer RNA
- Bring amino acids to the ribosomes for addition to the polypeptide chain
- 75 90 nucleotides long
- Internal anticodon (3-nucleotide segment) is complimentary to mRNA
codons
- tRNA and mRNA bind antiparallel to one another
ex. tRNA linked to Seranine pairs with codon AGU
in mRNA. The anticodon of the tRNA that pairs
with this is UCA
- Attached to 3’ prime end is an amino acid specific
to the anticodon distinctive structures
Cloverleaf - 2 dimensional Structure of tRNA
- Anticodon is at the bottom of the structure
- You could predict what the anticodon is because of
the genetic code. More than one codon that codes
for a protein.
- Amino acid attaches to the transfer end of the
tRNA it has to be charged amino acylation (the
addition of an amino acid)
- 3 nucleotides complementary to mRNA
- Wobble Hypothesis: the third nucleotide can change but still codes for the same
amino acid (most of the time)
L Shape 3 dimensional structures
- How it actually is formed in the body
Unlock document

This preview shows page 1 of the document.
Unlock all 4 pages and 3 million more documents.

Already have an account? Log in

Get access

Grade+
$10 USD/m
Billed $120 USD annually
Homework Help
Class Notes
Textbook Notes
40 Verified Answers
Study Guides
1 Booster Class
Class+
$8 USD/m
Billed $96 USD annually
Homework Help
Class Notes
Textbook Notes
30 Verified Answers
Study Guides
1 Booster Class