Biology 1202B Lecture Notes - Lecture 24: Epigenome, Methyl Group, Epigenetics

68 views6 pages
8 Apr 2019
Department
Professor
Wed, Apr. 3/19 Lecture 24: Epigenetics
Epigenetics: Study of changes in gene expression caused by other than changes to the DNA sequences
Epi (top), puts markers above the sequence
Genome can be viewed as the hardware and the epigenome is the software
Genes can be 'tagged (methyl group)' by our experiences - dynamic and can be inherited by
offspring (transgenerational inheritance)
Occurs on the cytosine nucleotide
o Exposure to environment and affect of the environment on the genes (mutations)
o Genome Is not very sensitive, epigenome is very sensitive and can go on or off the
epigenome, the methyl group can be added or removed based on the experience.
o Transgenerational inheritance (habits, tendencies can be inherited to off spring)
Tag tells the genome how to react, and they can be changed
Nurturing can alter nature
Epigenome is destiny, not genome
Unlock document

This preview shows pages 1-2 of the document.
Unlock all 6 pages and 3 million more documents.

Already have an account? Log in
2
Genetically similar, but have different epigenomes
The difference is in the diet the mother had when she was pregnant
It changed the promotor of the Agouti gene
DNA is not Destiny
Grew up without a mother were anxious, craved alcohol, were scared
Epigenome is beyond their control
Genes that were suppressed are normally active and genes that are normally active are
suppressed
Were not raised the way they were supposed to
Unlock document

This preview shows pages 1-2 of the document.
Unlock all 6 pages and 3 million more documents.

Already have an account? Log in

Get OneClass Notes+

Unlimited access to class notes and textbook notes.

YearlyBest Value
75% OFF
$8 USD/m
Monthly
$30 USD/m
You will be charged $96 USD upfront and auto renewed at the end of each cycle. You may cancel anytime under Payment Settings. For more information, see our Terms and Privacy.
Payments are encrypted using 256-bit SSL. Powered by Stripe.