Biology 1202B Lecture Notes - Release Factor, Alternative Splicing, Protein Targeting
Document Summary
Structure of rna: about 80% rna in a cell is rrna (ribosomal) rrna-protein complexes = where translation occurs. Each subunit is made of rrna and ribosomal proteins: mrna template for translation. Any errors in mrna will affect the protein you make trna (transfer rna) . Attached to 3" end is an amino acid specific to the anticodon distinctive. Internal anticodon sequence is complementary to mrna codon structure. Non-watson and crick bindings - there are some unusual bindings in trna. This gives it some wiggle room when binding they have room to move trna and mrna bind in an antiparallel manner: there are 3 sites in the rrna-protein complex. A site = aminoacyl site trna"s seek out the e, p and a sites. Translation using mrna to create polypeptide chains (long amino acid chains: 3 stages of translation. Met-trna with gtp bound to it and the small ribosomal subunit form a complex.