Biology 1202B Lecture Notes - Lecture 24: Reverse Transcriptase, Retrotransposon, Inverted Repeat

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Transposition may be cut or copy and paste. They don"t actually jump never in the air. May lead to altered function of gene/regulatory region. Transposons have is flanking central sequence (may contain genes) First identified (but not understood) in corn eukaryote. Retrotransposons move via reverse transcriptase (copy and paste) Retrotransposons use reverse transcriptase (rt) to copy and paste. Mutations in gag or env prevent formation of viral particle. Snp or sequencing analysis of a single genome. Determine probability of trait expression or disease risk. Recently possible due to cheap sequencing and microarray analysis. Used to receive information on snp association to various diseases. Does not meet standards to be a diagnostic test. Now can only be marketed as ancestry or informational purpose. Both arms of the adaptive immune system impaired. Caused by one of several different genetic mutations. Correcting a genetic disorder by supplying a functioning gene.

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