Biology 1290B Lecture Notes - Lecture 1: Natural Killer Cell, Adaptive Immune System, Innate Immune System
20 Oct 2015
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Document Summary
Role: protect body against bacterial toxins, viruses, parasites, and fungi. Leukocytes (white blood cells) are produced in the bone marrow. Granulocytes have a granular cytoplasm that contains digestive enzymes and other antimicrobial chemicals. Eosinophils contain toxic compounds to defend against multicellular parasites. Basophiles are similar to most cells, acting in allergic reactions. The lymphatic system is composed of cells and tissues essential to immune function. Lymph is the clear fluid surrounding tissue cells and fills intercellular spaces. The lymphatic system maintains and distributes lymphocytes. Mucous membranes that line digestive, respiratory, reproductive tracts cover. Second line of defense (innate immune system, germline encoded receptors- no adaptation to specific pathogens) Cytokines, hormone like proteins that mediate inflammation and complement proteins. Third line of defense (vertebrates only): adaptive immune system (adapts to defend against specific pathogens using variable receptors. B cells make antibodies that vary can make an antibody specific for any new antigen. T cells mediate cellular response using variable receptors.
