Biology 1290B Lecture Notes - Lecture 1: Tooth Enamel, Robin Warren, Barry Marshall

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Chapter 11: diseases of the oral cavity and the gastrointestinal system. The digestive system has an extensive indigenous microbiota. The digestive system is composed of two separate categories of organs (gastrointestinal (gi) tract & accessory digestive organs) Chemical, mechanical, and cellular defenses protect the gi tract from pathogen colonization. Our understanding of the human oral and gi microbiome is rapidly improving. The human gut microbiome initiative is helping to learn more about our gut microbiome. The resident normal microflora of the digestive tract. The esophagus is largely free of microbes as is the stomach because of its highly acidic environment , many bacteria do survive the stomach, and they transit to the small intestine. One bacterium found in the stomach can cause ulcers and cancer: helicobacter. Dr. robin warren and professor barry marshall proved most gastric ulcers are caused by h. pylori, drank heavy culture of h. pylori, which caused ulcers and were treated with antibiotics.

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