Biology 2601A/B Lecture Notes - Lecture 18: Nernst Equation, Atp Hydrolysis, Biological Neural Network

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Communication between cells, tissues and organs is critical for normal growth and development. In animals, this extends to coordination of locomotion and involves electrochemical signalling via a neuronal network. Neurons are specialized for producing and transmitting electrical signals (action potentials) Axons can be very long; nerves are bundles of axons: at the end of each axon there are synapses which is where the action of transmitting information takes place. Neurons and other cells maintain an electrical potential (voltage) across the membrane, which acts as an insulator. All cells have an electrical potential, more positive on outside than inside: because membranes are semipermeable, they represent a barrier to ion movement. Ion concentration differences combined with selective permeability of ion channels lead to an equilibrium voltage (chemical vs. electrical gradient) Ion pumps create and maintain ion gradients; resting potential generated by a single ion is predicted by the nernst equation.

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