Biology 3316A/B Lecture Notes - Lecture 13: Oncology, Autophagy, Brainstem
13 Jul 2019
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It starts off in embryos: there"s several types of medulloblatomas that form and they all tend to agree with what we are going to talk about. Focusing on hedgehog signaling: there is a link between autophagy and hedgehog signaling. We are presented with what the oncologist shows us: taking the mass out and finding the issue and see what"s normal. If everything is good, then you can proliferate and continue on your way. There is pro-survival with pi3k, akt, and lkb pathway. If everything is good, then you drive towards mtor. X: making a drug that doesn"t break down as easily because the cell doesn"t recognize it fully. It"s related to the small family of g-proteins. It is a gap or a gef (guanine nucleotide exchange factor): gef: is this acting to add in more gtp or acting to speed down the break down of.
