Biology 3316A/B Lecture 1: Advanced Cell Bio Notes Lec 1
9 Feb 2018
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Specialization of the cell membrane: biomembranes and lipid. Phospholipid heads polar (hydrophilic); phospholipid tails non-polar (hydrophobic) Integral membrane proteins span the length of the membrane, as do transport proteins (channels) Any lipid attached to membrane = glycolipid, any protein attached to membrane = glycoprotein. Peripheral proteins face one side of the membrane: phosphoglycerides. As short as 16 carbons, as long as 18 carbons; two fatty acid chains linked to a glycerol molecule via ester linkage (shown by black circle) Plasmalogen interesting case because it has an ether linkage (shown by blue circle) and ester linkage to protect cell from oxidative stress. Many different important phosphoglycerides including: phosphatidylethanolamine (pe, phosphatidylcholine (pe, phosphatidylserine (ps, phosphatidylinositol (pi, sphingolipids. Consists of a sphingosine molecule attached to a fatty acid chain via amide bond (shown by black circle) Can either be a sphingolipid or a glycolipid (when sphingosine is attached to a carb: sterols.
